When it comes to captivating journeys, few can compare to the route from Ho Chi Minh to the Mekong Delta. This enchanting voyage takes you through vibrant landscapes, cultural treasures, and unforgettable experiences. In this comprehensive guide, we will not only explore the distance between Ho Chi Minh and the Mekong Delta but also uncover the captivating attractions along the way. The Ho Chi Minh to Mekong Delta Distance The distance between Ho Chi Minh City and the Mekong Delta is approximately 175 kilometers (about 109 miles) as the crow flies. However, the true magic lies in the journey itself.